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Jing-Gung Chung Selected Research

Caspase 9

10/2013Citric acid induces cell-cycle arrest and apoptosis of human immortalized keratinocyte cell line (HaCaT) via caspase- and mitochondrial-dependent signaling pathways.
9/2012Diallyl trisulfide induces apoptosis in human primary colorectal cancer cells.
5/2012Antitumor effects of emodin on LS1034 human colon cancer cells in vitro and in vivo: roles of apoptotic cell death and LS1034 tumor xenografts model.
1/2012Triggering apoptotic death of human malignant melanoma a375.s2 cells by bufalin: involvement of caspase cascade-dependent and independent mitochondrial signaling pathways.
8/2011Benzyl isothiocyanate (BITC) and phenethyl isothiocyanate (PEITC)-mediated generation of reactive oxygen species causes cell cycle arrest and induces apoptosis via activation of caspase-3, mitochondria dysfunction and nitric oxide (NO) in human osteogenic sarcoma U-2 OS cells.
1/2011Danthron, an anthraquinone derivative, induces DNA damage and caspase cascades-mediated apoptosis in SNU-1 human gastric cancer cells through mitochondrial permeability transition pores and Bax-triggered pathways.
9/2010Houttuynia cordata Thunb extract inhibits cell growth and induces apoptosis in human primary colorectal cancer cells.
11/2009Aloe-emodin induces cell death through S-phase arrest and caspase-dependent pathways in human tongue squamous cancer SCC-4 cells.
1/2009Emodin induces apoptosis of human tongue squamous cancer SCC-4 cells through reactive oxygen species and mitochondria-dependent pathways.

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Jing-Gung Chung Research Topics

Disease

252Neoplasms (Cancer)
03/2022 - 01/2003
80Leukemia
05/2021 - 09/2003
43Lung Neoplasms (Lung Cancer)
03/2022 - 06/2003
43Neoplasm Metastasis (Metastasis)
10/2021 - 07/2007
32Mouth Neoplasms (Oral Cancer)
11/2019 - 09/2007
27Breast Neoplasms (Breast Cancer)
05/2018 - 01/2003
24Colonic Neoplasms (Colon Cancer)
12/2019 - 12/2005
23Melanoma (Melanoma, Malignant)
01/2021 - 12/2005
23Osteosarcoma (Osteogenic Sarcoma)
10/2019 - 01/2004
22Hepatocellular Carcinoma (Hepatoma)
01/2022 - 07/2007
22Body Weight (Weight, Body)
11/2020 - 09/2009
20Urinary Bladder Neoplasms (Bladder Cancer)
11/2019 - 01/2003
19Uterine Cervical Neoplasms (Cancer of the Cervix)
09/2018 - 05/2003
19Squamous Cell Carcinoma (Epidermoid Carcinoma)
03/2017 - 05/2003
18Carcinoma (Carcinomatosis)
07/2019 - 06/2003
15Glioblastoma (Glioblastoma Multiforme)
04/2021 - 11/2009
13Prostatic Neoplasms (Prostate Cancer)
12/2019 - 12/2005
13Mitochondrial Diseases (Mitochondrial Disease)
01/2017 - 01/2009
13Ataxia Telangiectasia (Louis Bar Syndrome)
10/2016 - 03/2010
12Tongue Neoplasms (Tongue Neoplasm)
12/2017 - 11/2007
11Liver Neoplasms (Liver Cancer)
01/2020 - 12/2005
9Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
06/2021 - 05/2008
8Stomach Neoplasms (Stomach Cancer)
10/2021 - 05/2005
8Skin Neoplasms (Skin Cancer)
04/2019 - 05/2004
8Nasopharyngeal Carcinoma
01/2019 - 09/2007
8Carcinogenesis
03/2017 - 06/2003
7B-Cell Lymphoma (Lymphoma, B Cell)
09/2020 - 11/2009
6Colorectal Neoplasms (Colorectal Cancer)
11/2020 - 01/2004
6Squamous Cell Carcinoma of Head and Neck
03/2017 - 09/2007
5Acute Promyelocytic Leukemia
01/2020 - 11/2006
5Blister (Bulla)
07/2017 - 04/2011
5Necrosis
05/2014 - 01/2006

Drug/Important Bio-Agent (IBA)

56Proteins (Proteins, Gene)FDA Link
06/2021 - 12/2005
48CaspasesIBA
03/2022 - 03/2007
28CurcuminIBA
04/2021 - 05/2003
28Caspase 3 (Caspase-3)IBA
09/2018 - 11/2004
25Matrix Metalloproteinases (MMPs)IBA
10/2020 - 11/2006
25Reactive Oxygen Species (Oxygen Radicals)IBA
01/2018 - 01/2006
24Biological ProductsIBA
01/2020 - 11/2004
23DNA (Deoxyribonucleic Acid)IBA
12/2016 - 05/2003
22Matrix Metalloproteinase 2 (Gelatinase A)IBA
05/2018 - 03/2006
22Messenger RNA (mRNA)IBA
11/2013 - 05/2003
18NF-kappa B (NF-kB)IBA
01/2021 - 05/2005
17AcetyltransferasesIBA
09/2012 - 01/2003
16bufalinIBA
03/2022 - 01/2012
16Pharmaceutical PreparationsIBA
05/2021 - 01/2008
16N-acetyltalosaminuronic acid (NAT)IBA
03/2006 - 01/2003
14Antineoplastic Agents (Antineoplastics)IBA
01/2020 - 07/2005
14phenethyl isothiocyanate (PEITC)IBA
09/2018 - 06/2010
14Complex MixturesIBA
11/2016 - 07/2004
13Cantharidin (Cantharides)IBA
10/2019 - 11/2010
13benzyl isothiocyanateIBA
11/2018 - 11/2009
13BerberineIBA
08/2018 - 11/2005
13Protein Serine-Threonine Kinases (Protein-Serine-Threonine Kinase)IBA
09/2015 - 03/2010
12FlavonoidsIBA
01/2019 - 02/2006
122-aminofluoreneIBA
03/2006 - 01/2003
11casticinIBA
09/2020 - 01/2016
11Gallic AcidIBA
09/2018 - 05/2009
11MethyltransferasesIBA
12/2016 - 07/2010
10Cytochromes c (Cytochrome c)IBA
09/2020 - 01/2009
10monocyte-macrophage differentiation antigenIBA
09/2018 - 11/2009
10DNA AdductsIBA
09/2012 - 01/2003
10aloe emodinIBA
04/2011 - 09/2003
9Complementary DNA (cDNA)IBA
07/2018 - 05/2003
9Caspase 9IBA
10/2013 - 01/2009
9Emodin (Archin)IBA
09/2012 - 01/2006
8QuercetinIBA
11/2018 - 02/2006
8Biomarkers (Surrogate Marker)IBA
01/2017 - 11/2011
8isothiocyanic acidIBA
01/2017 - 08/2011
8Caspase 8 (Caspase-8)IBA
12/2016 - 03/2009
8diallyl disulfide (diallyl disulphide)IBA
09/2013 - 07/2005
7AntioxidantsIBA
09/2021 - 01/2008
7Phosphotransferases (Kinase)IBA
06/2021 - 11/2011
7Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
02/2020 - 06/2009
7bisdemethoxycurcuminIBA
01/2020 - 11/2015
7Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA
09/2018 - 08/2011
7Phosphates (Orthophosphate)IBA
09/2018 - 11/2009
7AnthraquinonesIBA
05/2014 - 11/2009
7rheinIBA
05/2010 - 01/2007
6demethoxycurcuminIBA
04/2021 - 01/2015
6Ethanol (Ethyl Alcohol)IBA
07/2019 - 07/2007
6tetrandrineIBA
04/2019 - 04/2016
6Apoptosis Inducing FactorIBA
09/2018 - 10/2009
6CarcinogensIBA
03/2017 - 01/2005
6EnzymesIBA
01/2017 - 06/2003
6DAPIIBA
10/2016 - 12/2006
6diallyl trisulfideIBA
11/2015 - 06/2011
6danthronIBA
08/2012 - 11/2009
5Peptides (Polypeptides)IBA
01/2021 - 05/2013
5Extracellular Signal-Regulated MAP Kinases (Extracellular Signal Regulated Kinases)IBA
10/2020 - 01/2015
5Gefitinib (Iressa)FDA Link
11/2019 - 12/2016
5Apoptosis Regulatory ProteinsIBA
09/2018 - 08/2011
5endonuclease GIBA
11/2017 - 10/2009
5triptolideIBA
02/2017 - 02/2011
5AlkaloidsIBA
10/2016 - 03/2007
5allyl sulfideIBA
09/2013 - 12/2009

Therapy/Procedure

21Therapeutics
03/2022 - 01/2009
13Drug Therapy (Chemotherapy)
03/2022 - 01/2007
8Aftercare (After-Treatment)
02/2020 - 01/2006
7Chinese Traditional Medicine (Traditional Chinese Medicine)
03/2017 - 10/2009